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ICAR- NATIONAL RICE RESEARCH INSTITUTE
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What are we exploring?
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RICE PHOTOSYNTHESIS, STRESS MANAGEMENT, GENOME EDITING, CRISPR-Cas
Dr. Subhasis Karmakar joined this lab in 2020, and is working on diverse areas in plant genome editing. He focuses on developing new genome editing tools using novel effectors and applying them for crop improvement. He is one of the pioneer members in lab establishment.
CRISPR-Cas9 enable us to manipulate plant genetic codes for generating new traits. Debasmita is working as a PhD scholar since 2021. She is devoted on developing a novel base editor. Additionally, Debasmita is involved in increasing the harvest index of rice through genome editing.
Priya is associated with this lab as a PhD scholar. She is working on a knock-out project to improve rice productivity. Also she is involved in Cas12 associated tool development.
Rice root exudates play an important role in rhizosphere microbe interactions that may be helpful to both plants and microbes. Romio is a Project Associate I in this lab, working on role of root exudated flavonoids that may stimulate the diazotroph population favouring more biological nitrogen fixation, leading to more nitrogen use efficient rice plants.
Dr. Tanmoy joined our laboratory as a research associate in C4 Project. He is leveraging the powerful prime editing system to introduce advantageous gene mutations, aiming to enhance gene expression and significantly improve rice.
As we all know rice, a C3 plant, contains all the C4 genes, but the functions of these genes are unknown. Dr. Abhiram is now trying to understand the functions of C4 genes present in rice by developing mutants using CRISPR-Cas9 through genome editing technology. He is also standardising tissue culture regeneration media of several recalcitrant Indica rice varieties.
First developed in 2019, prime editing (PE) is a versatile and precise genome editing technology that can make diverse types of gene edits, including small substitutions, insertions, deletions, and combinations of all. Sonali joined the lab in 2020 as a DST Inspire Fellow. She is working on improving PE efficiency in plants by fusing different DNA repair proteins. Apart from that, Sonali is applying prime editing to modify C3 genes in rice to behave like C4 genes.
Genome editing technology has been pounced by Base Editors as they have paved the way to introduce point mutation in the genome. Avinash is associated with this lab as a PhD scholar. He is working on Base Editing technology. His area of research includes expanding the target range by developing a novel Base Editor(BE) and installing agronomically relevant point mutations in rice.
Chandana is associated with this lab as a Project assistant in 2023. She is working to increase nitrogen use efficiency in rice through genome editing which can help in plant growth, grain production and quality. It can reduce dependence on excessive use of external nitrogen fertilizers in the rice fields to enhance the soil health, air as well as water quality.
YOU CAN BE THE NEXT HERE!
